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SRE XS kit

102-208-200 (previously SS-100-121-01)
Reagents to complete depletion/size selection of DNA <10 kb
In stock
Product Details

The SRE XS kit uses size-selective precipitation to dramatically reduce short reads below 5 kb.

This kit is more tolerant of fragmented DNA and low DNA concentration than its siblings. It also features a higher recovery efficiency (50–90%).

Short DNA fragments <10 kb are progressively depleted (i.e., depletion efficiency increases as DNA gets shorter). DNA <4 kb are nearly completely removed. Depletion range estimated based on sequencing read length distributions and gel electrophoresis.

The read length enhancement is dependent on:

1. the amount of short DNA present in the input DNA

2. the amount of long DNA present in the input DNA

Overall recovery efficiency is dependent on:

1. the quality of the input DNA

2. input DNA concentration

Expect to recover 50–90% of your HMW DNA.

This kit can be used with HMW DNA, fragmented DNA, sheared DNA, and PCR amplicons.

Processing requires only a simple centrifuge step and two wash steps. Total process time is one hour.


1. Buffer SRE XS — 1 mL

2. Buffer EB — 5 mL

Sufficient for at least 16 standard purifications.

Procedure and checklist

SRE kit



All kits are guaranteed for one year from the date of purchase.


Patents / Terms and conditions

International customers

Additional import duties/taxes/fees (i.e., VAT or GST where appropriate) will be payable directly to the import broker FedEx.

To facilitate customs, Australian customers should provide an appropriate import permit.

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