Journal Article Details the Use of Ligo-miR EZ for Quantifying miRNA Copy Number

Circulomics has recently published its first article describing the use of Ligo-miR technology for multiplexed miRNA profiling. The article entitled "Determination of absolute expression profiles using multiplexed miRNA analysis" was published in PLoS ONE with collaborators Dr. Tza-Huei Wang, Dr. Stephen Meltzer, and Dr. Kevin Yarema of Johns Hopkins University as well as Dr. Carlo Croce of Ohio State University. This paper details the simplest version of Ligo-miR. Ligo-miR EZ uses fluorescent PAGE detection to perform up to 24-plex profiling and requires only a thermal cycler and PAGE system, equipment readily available in most molecular biology labs. It shows high correlation to both Agile

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